I-Cannabis ethembisa Izinzuzo Zezempilo Ze-Raw Cannabis

Luhlaza Okwengca Nabani Na?

Ngoko ke, yintoni imifuno kunye necannabis ekufuneka uyenze omnye nomnye? Ewe, imifuno idla ngokuchazwa ngokuba "yinxalenye etyiwayo yesityalo esilinyiweyo" kwaye ityiwa ngokutya (okanye isiselo). Idla ngokubhekisela kwingcambu, isiqu, igqabi, okanye intyatyambo yesityalo. Eminye imifuno ingatyiwa ekrwada ngelixa ezinye zifuna ukuphekwa ukuze zityiwe. Nangona kunjalo, yinto eyaziwayo ukuba xa iziqhamo ezithile nemifuno zitshiswa, ziphulukana nee-enzayim eziluncedo kunye nezondlo ezikwinkqubo. I-Cannabis ikwabelana ngesithethe ngemifuno yemveli.

Iindlela zokwenza amalungiselelo asekelwe kwi-cannabis asekelwe kwiziphi iinzuzo ezifunwa sisityalo. Kwiminyaka yakutshanje abanye baye baqalisa ukukhuthaza ukusetyenziswa kwe-cannabis ekrwada ngeenjongo zonyango, bexela ukubaiikhompawundi ezisebenzayo ezifumaneka kwifomu yayo ekrwada nazo zinemiphumo ekhethekileyo.

Kwimeko yokucima i-cannabis, umphunga, amayeza, iikhrim kunye ne-oyile ephakamileyo, inkqubo ebizwa ngokuba yi-decarboxylation idla ngokuthatha indawo, nto leyo ethetha ukuba izinto zezityalo ziveliswe bubushushu. Xa iqondo lobushushu linyuka, iatom yekhabhon ishiya ikheyini yekhabhoni, ikhupha icarbon dioxide (CO2). Oku kuyimfuneko kwi-cannabis-avela kwi-cannabis ukuze ukwazi "ukulingana" KWI-CB1 kunye NE-cb2 cell receptors kwinkqubo ye-endocannabinoid yengqondo kunye nomzimba.

Ngenxa yokuba isisu asivelisi ubushushu ngokwaneleyo i-athomu ye-carbon ukuze yahlule kwi-molecule ye-cannabinoid, uhlobo olungenakukrakra LWE-THC ( i-tetrahydrocannabinol, enye yezithako eziphambili kwi-cannabis ) ayikwazi ukubopha kwi-receptors YE-CB1 kwi -ubuchopho obujongene neziphumo ezinxunguphalisayo ze-cannabis. Nangona uphando nge-cannabis ekrwada lusenokuba khona, abanye bakholelwa ukuba i-asidic cannabinoids (ekrwada, engashiywanga) isebenza ngendlela eyahlukileyo.

I-THCA kwi-cannabis ekrwada ayikho i-psychotropic, ngoko i-cannabis ekrwada ayiguquki engqondweni kwaye ayinyulanga nantoni na ephezulu.

Intshukumo yecannabis ekrwada

Enye yezona zinto zaziwa kakhulu zokusetyenziswa kwe-cannabis ekrwada Yi-California esekelwe Kwidkt William Courtney, ezakhe zaqala ukuboniswa ngempumelelo enkulu ukuba inkosikazi yakhe — oye wasweleka kwi — systemic lupus, isifo samathambo kunye nezinye izigulo-ezinamava, ezibizwa ngokuba kukuphuculwa kwempilo ephawulekayo emva kokuqala ukutya ama-cannabis amagqabi kunye neentlalutye. Ngokuvumelana nayeukufumana, ukutya i-cannabis entsha ngale ndlela kuvumela ukuba isigulana sandise ukutya kwazo yonke imihla nge-cannabinoids kakhulu, bonke ngelixa sigwema nayiphi na imiphumo ye-psychotropic / ephezulu.

 

Oku kubalulekile xa ukhulisa umba wokusetyenziswa kwe-cannabis kwaye ucingela ukuxhatshazwa, ngakumbi ngokubhekiselele kubantwana, ukwenzakala kakhulu kunye nabadala. Ukusetyenziswa kwe-cannabis ekrwada kuyakunciphisa oku, kwaye kungabonwa njengenye yeendlela ezigqibeleleyo zokuphepha nayiphi na imiphumo engafunekiyo, ngelixa isafumana inzuzo engenakubalwa kwisityalo.

I-cannabis ekrwada: indlela yokusebenza

Abacebisi, abafana Nodkt Courtney, bika ukuba i-crude cannabinoid inika izibonelelo zexesha elide, ezingenakukwazi ngokubanzi ukuphelisa uphawu ngokukhawuleza, nangona ezinye iziphumo zingabonwangokuzalana ngokukhawuleza. Ii-acid ze-Cannabinoid zigcinwa kwi-adipose tissue (amafutha omzimba) kwaye zingathatha iiveki eziliqela (mhlawumbi ezine ukusa kwesibhozo) ukuze inyama ye-adipose yomzimba ingagcwala ngokupheleleyo. Nje ukuba inyama ye-adipose isebenzise ngokupheleleyo i-cannabinoid acid, ifuthe le-cannabis ekrwada iqala.

 

Uphando oluncomekayo, njengaleyo Kagqr Ruth Ross, Usihlalo Kwisebe Le-Pharmacology & Toxicology Kwiyunivesithi Yasetoronto, eququzelela iqela lophando, wafumanisa ukuba i-CBDA KUNYE NE-cbga cannabinoid acid bobabini banempembelelo engahambiselani (yokuvimbela) emzimbeni onegalelo ekuphinda-phindwe ngokukhawuleza kweeseli zomhlaza, kunye nokubona intlungu kunye nokuvuvukala. Ngokuvimbela uphawu kulezi zamukeli, ama-cannabinoid acid kuthiwa anawoiimpawu zomhlaza ezilwa nomhlaza ziyanceda kwakunye nokudambisa iintlungu eziboniweyo kunye nokukrala emzimbeni. Uphando oluninzi luyafuneka kule ndawo ukuhlola amathuba apheleleyo e-cannabis kule ndawo.

Zithini I THCA NE CBDA?

Nangona uphando oluninzi lugxile KWI-THC NE — CBD, xa kuthelekiswa okuncinci kwaziwa nge-asidi-THCA (i-tetrahydrocannabinolic acid) kunye NE-CBDA (i-cannabidiol acid). Into yokothusa abaninzi, kukuba i-cannabis ekrwada-ingakumbi xa intsha-eneneni iqulethe I-THC kunye NE-CBD encinane kakhulu, kunokuba ininzi ye-acid (THCA kunye NE-CBDA). Isityalo se-cannabis sivelisa kuphela i-cannabinoids ngefomu ye-asidi ethe yaguqulelwa KWITHC NAKWI-CBD emva kokutshisa okanye ukuvuthwa. Decarboxylation okuukuphendula kwamakhemikhali okujongene noxanduva lwale nguqu. Uma kushiywa ngendlela yemvelo, I-THCA NE-CBDA azinayo imiphumela yengqondo, kodwa kucetyiswa ukuba ube nemiphumela efana nempilo kumalungu abo angcono.

 

I-THCA yi-TRPA1 enamandla kunye NE-TRPM8 receptor antagonist, enokucacisa impembelelo yayo ye-analgesic kunye nendima ebalulekileyo kunyango lomhlaza weprostate. Kwakhona I-THCA ineempawu ze-antiemetic kwaye ikhusela i-dopamine neurons ekwehleni, enokuthi incede kakhulu kunyango lwesifo Sikaparkinson.

 

Ucwaningo luveze ukuthi I-THCA nayo ingakwazi ukuvimbela ukukhiqizwa kwemibandela ye-necrosis (TNF) egazini.

 

ITNF yiprotheyini esemzimbeni enegalelo ekukrala. Kulabo kulaboimpilo, idlala indima ephambili kumajoni omzimba, inceda umzimba ukuba ubeke ezawo ukhuselo kunye nokuhlasela iintsholongwane ezingenayo kunye neentsholongwane, kwakunye nokuphilisa izicubu ezonakeleyo. Kodwa ke, abantu abanezifo ezithatha inxaxheba kwizifo zokuhlaselwa kweeseli eziphilileyo ngamajoni omzimba, nangona kunjalo, iqondo eligqithisileyo LE-TNF egazini lingakhokelela ekuqalekeni ukukrala okubukhali kwaye kubangele umkhuhlane, ukufa kweeseli kunye nesifo se-arophy. Ummiselo onganelanga ukwayanyaniswa nezifo ezininzi, kuquka isifo se-Alzheimer, udandatheko, isifo se-sclerosis esininzi, isifo sokukrala kwamathumbu kunye neminye imihlaza.

 

I-THCA yinto enkulu yokulwa nokukrala kuba ikwavimbela i-cyclooxygenase 1 ne-2

(COX-1 KUNYE NE COX-2). Ukunciphisa IBHOKISI yindlela leyo analgesics ezininzi eziqhelekileyo (ezifana ibuprofen kunye aspirin) umsebenzi, ngaloo ndlela ukunciphisa ukukralaneentlungu.

 

I-CBD inezimpawu ezifanayo NJENGE-THC KWI-TRPA1 ne-TRPM8 receptors, futhi ingakhuthaza i-enzyme emzimbeni odlala indima ebaluleke kakhulu ekulweni nokuvuvukala. Kwakhona I-CBDA inamandla okulwa neeseli zamathumba ezijingayo kakhulu kwezinye iiseli zomhlaza webele. Inefuthe kwi-serotonin receptors, enokuchaza inxalenye yezinto ezichasayo zesicatshulwa. Abanye abaphandi banika iipropati zabo ezilwa nokukrala njengoko zizi-2 ukuya kwezi-4 ezinamandla kunezo zaziwa NGOKUBA YI-THC NE-CBD.

 

Kukho enye impahla ethakazelisayo ye-cannabinoids: i-hydrophilic, ithetha ukuba i — soluble yamanzi ngokuyinxalenye, ngokungafani ne — decarboxylated cannabinoids-THC, CBD-engeyiyo.

Izinto eziluncedo ezinokwenzekaka matshiof january

Into yokuba I-THCA ayinayo nayiphi na imiphumo yengqondo ingabonwa njenge-drawback enkulu kubasebenzisi abathile bezonyango, njengoko ingasebenzi inkqubo ye-endocannabinoid kwimveli. Enhliziyweni yophando lwe-cannabis oluninzi kukusebenza kwale nkqubo ekhethekileyo yebhayoloji, neengcali ezininzi, kuquka Ugqr Courtney, uthi unoxanduva lokuphumeza iimpawu ekwaziwa ngazo i-cannabis.

Umzekelo, iimpawu zeentlungu neengxaki zemithambo-luvo zilawulwa ngqo ngumonzakalo we-cannabinoid engqondweni. Unyango lwecannabis ekrwada alunakuba luncedo kwezi meko kodwa akukho bani owaziyo ukuqiniseka.

Ngoko ke, olunye uphando luyafuneka kwiziphumo ze-cannabis ekrwada yaye okwangoku, izigulana ziya kufuneka zifumaneiyothuse / iyunithi eyoyikekayo kwindawo ekhuselekileyo nenhle.

 

Enyanisweni, uphando lwakutshanje luye lwacebisa ukuba i-cannabinoid acid ingachaphazela iindawo ebezingafani ngaphambili ze-endocannabinoid system, kodwa umsebenzi omninzi uyafuneka kule ndawo..

Indlela yokwenza i-cannabis juice ekrwada?

 

Ukubeka zonke iintloko ze-cannabis ze-flower ezomileyo kwi-blender aziyi ukudala isiphumo esifunekayo — mhlawumbi ngencasa, okanye ngefuthe. I-cannabis ekrwada esandul ' ukuchathwa kwaye ikhule kakuhle i-cannabis ifanelekile njengejusi esebenzayo. Nangona kunjalo, kubalulekile ukuba unakekele ngokukhethekileyo ukuthintela naziphi na izinto zezityalo ezinokudibana nezitshabalalisi okanye ezinye izinto ezinetyhefu zezityalo.

 

Nazi iingcebiso eziphambili zokugcina engqondweni xa usenza i cannabis ekrwadamolo:

 

  • Njengezinye juices imifuno: itsha ngcono
  • Njengoko kuchaziwe ngasentla, i-cannabis eyomileyo ayilungelanga ukwenza i-cannabis juice
  • Iingcebiso jikelele zibonakala zithanda ukuxuba malunga namagqabi 1-15 kunye ne-2 enkulu eluhlaza ngosuku
  • Iintyatyambo ezikrwada ziintyatyambo ezivuniweyo xa idlala LETHC ziguqulelwa ( hayi amber ngombala )
  • Kucetyiswa ukuba uxubushe eminye imifuno okanye iziqhamo, ukuze kuncitshiswe ubukrakra obuzalwa yi-cannabis ekrwada. Ukhetho oludumile yi-carrot juice, futhi ijusi ye-1 ingxenye ye-cannabis ibe yi-10 izingxenye ze-carrot juice ratio yisiqalo esihle
  • Yahlula ijusi ibe ngamacandelo amathathu kwaye udle isidlo ngasinye okanye ufake isikhongozeli esatywiniweyo kakuhle kwisikhenkcezisi ukuya kuthi ga kwi 3iintsuku.

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