Igama elithi psychedelic laqanjwa ngu-psychiatrist Humphrey Osmond owaveza Ukuba Lifundiswe Enew York Academy Of Sciences ngo-1957. Avela amazwi isigrike izangoma, nto leyo ethetha umphefumlo okanye ingqondo, kwaye uchaze oko kuthetha 'ukubonakalisa'.
Kukho iintlobo ezahlukeneyo zezinto zengqondo. Ezinye zenzeka ngokwemvelo kwizityalo ezifana nefungi kunye necacti. Abanye bayahlanganiswa futhi bahanjiswa ngamaphilisi, iphepha le-blotter, ama-powders nokunye.
Izangoma ziye zasetyenziswa amawaka eminyaka ziinkcubeko ezahlukeneyo kwihlabathi jikelele kwimiphumo yabo engaqondakaliyo kunye engokomoya. Ezi zinto ziye zafundwa ngoososayensi, iingcali kunye namagcisa ukususela ngeminyaka yoo-1930 kwaye sele zivaliwe phantsi Kwengqungquthela Yezizwe Ezimanyeneyo Kwizinto Zengqondo, kwaye zafumana umdla ohloniphekileyo oye wavalwaukukhula ukususela ngowe-1970.