I-DMT inokwenza i-hallucinations ebonakalayo kunye neyovayo, kunye ne-euphoria, abafundi abahlanjululweyo, ukunyuka kwentliziyo kunye noxinzelelo lwegazi, isiyezi, ukulungelelaniswa kwemoto, isicaphucaphu, ukuxhalaba kunye ne-paranoia.
Abanye abasebenzisi bexesha elide bafumana i-flashbacks kwiinyanga okanye iminyaka emva kokusetyenziswa kwaye banokufumana iziqephu ze-psychosis, ezibandakanya ukuphazamiseka kwemizwelo, iingcamango ezingalungelelananga kunye ne-paranoia.
I-DMT yenza amava e-psychedelic xa kusetyenziswe umthamo ubuncinane we-0.2 mg / kg. Ukuqala kwayo kukhawuleza kakhulu xa itshaywa, kunye neziphumo ezivakalayo emva kwemizuzu emi-2 emva kokuba ityiwe kwaye ichithekile ngokupheleleyo emva kwemizuzu eyi-15 ukuya kwe-20. Ukusezela i-DMT exutywe kulwelo lweepeni zevape luhlobo olutsha lolawulo ekuthiwa yindlela elula kakhulu yokusetyenziswa enemibono eqikelelwa kakhulu okanye ebukhali ngakumbi kunaxa isetyenziswe ngeendlela eziqhelekileyo, ngokuxhomekeke kwithamo.
I-DMT ikhona amakhulu eminyaka, kwaye yayisaziwa entshona ngexesha le-1980 kunye ne-1990s nguTerence McKenna kunye no-Rick Strassman, ababhala 'i-DMT: I-Molekyuli yoMoya'.