Izifundo kunye novavanyo lukhokelele kwingcinga yokuba ukungeniswa nje kwesityalo esinye kunokubangela ukupheliswa ngokupheleleyo kweempawu zokurhoxa kwamanye amachiza, kwanokunciphisa ukunqwenela. Ngokufanelekileyo, i-ibogaine yacetywa njengechiza elisebenzayo ngokuchasene nokulutha i-heroin, i-cocaine, i-methadone, utywala kunye nezinye iziyobisi ezineempawu zokurhoxa. Ikwafunyaniswe ukuba iyasebenza ekunciphiseni ukuxhomekeka kwenikotini kwaye ithathwa njengenamandla aphezulu onyango lwengqondo, kodwa la mabango ayaphikiswa.
I-Ibogaine i-alkaloid evela kwintsapho ye-indole esetyenziselwa izicwangciso zonyango kunye nezingezona zonyango ukunyanga ukusetyenziswa kakubi kwe-opioid. Kuye kwadibaniswa nokunciphisa ukurhoxiswa kwe-opioid kunye neempawu zokurhoxiswa kweziyobisi kwizigulane ezingakhange zizuze kwezinye iindlela zonyango. Indlela esebenza ngayo ayikaqondwa ngokupheleleyo. Ukuza kuthi ga ngoku, akukho zifundo ezinokuthi zipapashwe kwisiphumo sokuthatha unyango lwe-ibogaine ekusebenziseni iziyobisi.
