Iziphumo ze-hallucinogenic ze-ketamine zafunyanwa ngokusetyenziswa kwayo kwi-anesthesia kunye nokuvuza kwayo esitratweni kunye nokusasazeka kokusetyenziswa kwayo kokuzonwabisa kunye neziyobisi ezilandelayo. Uphononongo lweengxelo ezivela koogqirha kunye nabaphandi lubonisa ukuba malunga ne-40% yezigulane, imizuzu embalwa emva kokulawula i-substance intravenously okanye intramuscularly, i-hallucinations ebonakalayo kunye ne-auditory, ukuphazamiseka kunye nokuziphatha okungenangqondo kwe-schizophrenomimetic kwenzeka, edla ngokuchithwa emva kwemizuzu engama-45-60.
I-dissociative state psychedelic state that ketamine induces ifundwe ngokucokisekileyo kwaye inzulu kwiimvavanyo ezenziwe ngu-American psychiatrist, neuroscientist kunye ne-psychonaut uProf John Lilly. U-Lilly wenze ingxelo ecwangcisiweyo malunga neziphumo ezizimeleyo ezivela kubudlelwane bokuphendula idosi (ecacisiweyo kwincwadi yakhe ethi Ketamine Dreams and Reality) ngovavanyo alwenzileyo kuye, ngesiqhelo ngelixa engaphakathi kwigumbi elikwanti lokudada. Iingxelo zokuqala zikaLily zibe negalelo elikhulu ekuqondeni utshintsho oluphawulekayo kwingqondo kunye nombono owenziwe yi-ketamine.