Iziphumo ze-Mescaline zivakalelwa malunga neeyure ze-1-2 emva kokungena, zihlala kwimizuzu engama-30-60 kwaye emva koko zichithe kwi-comedown ethatha malunga neeyure ze-3-5. Iziphumo ziyafana nezinye izinto zengqondo, kunye namava okubonakalayo anamandla ngakumbi. Ezi ziphumo ziquka ingqiqo yokuqonda, ukuphuculwa kombala, iimbono ezibonakalayo kunye nemibono, i-euphoria, ukuvuswa, ukunyuka kwe-touch sensitivity, i-synesthesia, imeko yephupha kunye nokunyuka kwengqondo kunye nokucinga okungaqondakaliyo ukuya kwinqanaba elipheleleyo kumava angaqondakaliyo.
Ezinye zeziphumo zomzimba ziquka ukuncipha kokutya, ukuguqulwa kokubona ixesha kunye nenyani, ukuhlanjululwa komfundi, ukungcangcazela, umnqweno wokuchama kunye nokungazinzi.
Ukwembiwa kwezinto zakudala kumazantsi e-US, eMexico nasePeru kuqinisekisa ukusetyenziswa kwe-cacti equkethe i-mescaline iminyaka engaphezu kwama-6000. I-Mescaline yinto eqhelekileyo kwiindidi ze-cacti, ezifumaneka ikakhulu kwi-peyote kunye ne-San Pedro cacti.
