Kweli phepha uza kufumana uluhlu loxinzelelo lwecannabis oluqulethe uhumulene. Humulene yiterpene efumaneka rhoqo kumagumbi kwaye inika ibheringi incasa kunye nevumba lomhlaba, iinkuni kunye nesiqholo. Ngenxa yoko uxinzelelo olumandla lwenkanunu cannabis badla ngokuthiwa ukwabelana ngezi mpawu inye. Enyanisweni, iterpene ithatha igama layo Ukusuka Humulus Lupulus, ekwabizwa ngokuba sisityalo samagosa.
Nangona kunjalo, humulene ukwasetyenziselwa iminyaka engamakhulu-khulu Kwizenzo zonyango Lwasempuma. Uphando lwangoku luyifumene ukuba ilusebenzisekayo ukulwa nokukrala, amayeza okubulala iintsholongwane nokucinezelwa ukutya okunesondlo. I-terpene exhaphakileyo kwi-cannabis kwaye kubonakala ngathi ikwimigangatho ephezulu kwi-caryophyllene etsaleka ngamandla ye-cannabis.
Humulene ifumaneka kwi-oyile emininzi ebalulekileyo yonyango, njenge-Balsam Fir Miri, ekholelwa ukuba nendima esebenzayo ekulweni kwamaqhuma ngenxa yokukwazi ukuvelisa Iintlobo Ze-Oksijini Ezisebenzayo (ROS). Kwakhona inendima yokudlala kwi-pharmacokinetics, uphando lwendlela ukufunxa umzimba, ukusasazeka, imetabolises kunye neziyobisi ezigqithisileyo, njengoko ibonise ukuba inakho ukusasazwa ngokukhawuleza emzimbeni. Nangona kunjalo, inkoliso yokokuba oxinzelelo lwecanabis luqulathe humulene nalo lunganikezela nangamanani eempawu ezamkelwa ngonyango.
